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EPTRI Open Meeting

The EPTRI Open Meeting was held remotely on the 2nd-3rd of April 2020 to guarantee the safely participation of the participants and the possibility to join and contribute to this crucial meeting.

The event has been the occasion to sum up the activities and the goals achieved as well as to discuss the challenges of the future EPTRI’s work.

The first part of the meeting provided an overview of the activities carried out so far in the project, together with a description of the future EPTRI architecture in terms of governance model, IT structure, services and organisation, being part of the design of the future infrastructure. Description was also presented of the centralised services provided at central hub level and of the integrated services based on the facilities and competences of the Institutions and research units that will constitute the thematic research platforms.

An open meeting took place in the morning of the second day with 13 presentations selected through a Call for Abstracts launched on February, on several topics related to the research areas of EPTRI. All the posters selected by the EPTRI Scientific Committee are published as teaser videos of 3 minutes and all the selected oral presentations are published as 10 minutes videos on the EPTRI website and on our YouTube channel.

A dedicated session on the EPTRI common services in collaboration with other RIs and the importance of the networking and outreach took place in the afternoon of the second day.

Here below you can see the scientific agenda of the meeting and the recordings of the meeting sessions.

 EPTRI Open meeting- First day morning session

 EPTRI Open meeting- First day afternoon session

 EPTRI Open meeting- Second day morning session

 EPTRI Open meeting- Second day afternoon session

Here below you can find the presentations of the EPTRI Open meeting in pdf format.

Session 1

The EPTRI project challenges
The EPTRI project challenges

D. Bonifazi

EPTRI governance and business model
EPTRI governance and business model

G. Migliaccio

EPTRI process towards ESFRI
EPTRI process towards ESFRI

M. Lupo

EPTRI Central Hub and Single Access Point
EPTRI central hub and single access point

F. Bonifazi

EPTRI Advisory Board and centralised services
EPTRI advisory board and centralised services

A. Ceci

Session 2

Paediatric Medicines Discovery Platform
Thematic Research Platform on “Paediatric Medicines Discovery”

E. Mikros

Thematic Research Platform on Paediatric Formulations
Thematic Research Platform on “Paediatric Formulations”

C. Tuleu

Biomarkers and Biobanking platform
Thematic Research Platform on “Paediatric Biomarkers”

M. Phylactides

Thematic Research Platform on ‘Developmental Pharmacology
Thematic research platform on "Developmental Pharmacology"

S. de Wildt

Session 3

Human fibro-adipogenic precursor cells as a new tool for investigating antifibrotic drugs in muscular dystrophies
Human fibro-adipogenic precursor cells as a new tool for investigating antifibrotic drugs in muscular dystrophies

J. Diaz-Madera

In silico methodologies and tools for predicting developmental toxicity
In silico methodologies and tools for predicting developmental toxicity

C. Altomare

Functional characterization of two genes deleted in Phelan McDermid Syndrome: SHANK3 and SULT4A1
Functional characterization of two genes deleted in Phelan McDermid Syndrome: SHANK3 and SULT4A1

C. Verpelli

The neonatal and juvenile Göttingen Minipig: a useful model for paediatric drug development
The neonatal and juvenile Göttingen Minipig: a useful model for paediatric drug development

S. Van Cruchten

Session 4

Institute of Pediatrics, Obstetrics and Gynecology: review, experience and prospective research
Institute of Pediatrics, Obstetrics and Gynecology: review, experience and prospective research

R. Marushko

Autism Spectrum Disorder: Linked-Read Sequencing reveals new and undetected variants
Autism spectrum disorder: linked-read sequencing reveals New and undetected variants

A. Mezzelani

Child-appropriate multiplex mass spectrometric assay solution to reliably monitor the maturating renin- angiotensin-aldosterone-system und the adjoining kinin-kallikrein-system in low sample volumes
Child-appropriate multiplex mass spectrometric assay solution to reliably monitor the maturating renin- angiotensin-aldosterone-system und the adjoining kinin-kallikrein-system in low sample volumes

B. Burckhardt

Drug safety in translational paediatric research – How to anticipate and manage treatment related risks
Drug safety in translational paediatric research – How to anticipate and manage treatment related risks

B. Aurich

ntestinal TCRγδ+ T cells and IL-4+ T cells: biomarkers to evaluate the transition from potential to acute celiac disease in paediatric patients
Intestinal TCRγδ+ T cells and IL-4+ T cells: biomarkers to evaluate the transition from potential to acute celiac disease in paediatric patients

C. Gianfrani

Session 5

In silico modelling and simulation for dosage selection in pediatric patients including neonates
In silico modelling and simulation for dosage selection in pediatric patients including neonates

E. Jacqz-Aigrain

Investigation and development of propranolol hydrochloride oral solid formulations designed for paediatric patients
Investigation and development of propranolol hydrochloride oral solid formulations designed for paediatric patients

N. Denora

Session 6

Breath-Triggered Aerosol Release and Real-Time Determination of the Delivered Aerosol for (Pre)term Neonates
Breath-triggered aerosol release and real-time determination of the Delivered aerosol for (Pre)term neonates

F. Wiegandt

EPTRI Communication and Advocacy
EPTRI communication and advocacy

B. Nafria

ID-EPTRI Open Meeting
EPTRI Outreach and Networking

D. Athanasiou

Paediatric ELSI common service in collaboration with BBMRI
Paediatric ELSI common service in collaboration with BBMRI

M. Mayrhofer

EPTRI-ELIXIR common service "Paediatric Data Interoperability”
EPTRI-ELIXIR common service "Paediatric Data Interoperability”

P. Martelli

EPTRI underpins medicines development for Paediatric Clinical Studies
EPTRI underpins medicines development for Paediatric Clinical Studies

M. Turner

EPTRI next steps
EPTRI next steps

D. Bonifazi