| USER |
USER INSTITUTION |
TITLE |
RAPP / CO-RAPP |
AB ASSESSMENT |
| Emmanuel Mikros (Internal user) |
Research and Innovation Center in Information Communication & Knowledge Technologies (ATHENA), Greece |
Discovery of new therapeutic agents for the treatment of Duchenne muscular dystrophy |
Dimitrios Athanasiou / Catherine Knibbe |
Positive |
| Marina Kleanthous (Internal User) |
Cyprus Institute of Neurology and Genetics (CING), Cyprus |
Identification of biomarkers for the segregation of paediatric beta thalassaemia patients responding to drug Hydroxyurea |
Oscar Della Pasqua / Dimitrios Athanasiou |
Positive |
| Evelyne Jacqz-Aigrain, Saskia de Wildt (Internal users) |
Department of pharmacology and pharmacogenetics – Assistance Publique – Hôpitaux de Paris (AP-HP), France, Department of Pharmacology-Toxicology – Radboud University Medical center (RUMC), The Netherlands |
Melatonin administered during pregnancy as a potential neuroprotective agent against neonatal brain damage |
Adriana Ceci / Catherine Tuleu |
Positive |
| Catherine Tuleu (Internal user) |
School of Pharmacy – University College London (UCL), UK |
Preparing a newly developed active pharmaceutical ingredient (API) for Phase 1 trials: enhancing the solubility for better bioavailability, improving the taste to allow its formulation into a wide range of oral dosage forms and assessing modifications carried out to validate the solubility and taste improvements made |
Giovanni Migliaccio / Catherine Knibbe |
Positive |
| Claudia Scotti (External user) |
Department of Molecular Medicine, Unit of Immunology and General Pathology, University of Pavia, Italy |
A protease-resistant Escherichia coli asparaginase with outstanding stability and enhanced anti-leukaemic activity in vitro: from bench to bedside |
Graziano Pesole / Oscar Della Pasqua |
Positive |
| Giuseppe Pontrelli, Oscar Della Pasqua (Internal users) |
Bambino Gesù Paediatric Hospital (OPBG), Italy, Clinical Pharmacology – University College London (UCL), UK |
MoSe2. Improved diagnosis and model-based dosing algorithms for antibiotic therapy in neonatal and paediatric sepsis. |
Adriana Ceci / Dimitrios Athanasiou |
Positive |
| Claudio Franceschi (External user) |
University of Bologna, Italy |
Precision Personalized Paediatric neuroPsychiatry (4P) |
Giovanni Migliaccio / Dimitrios Athanasiou |
Positive |
| Moshe Gavish (Internal user) |
Faculty of Medicine, Rappaport Institute for Research in the Medical Sciences – Technion, Israel Institute of Technology, Israel |
Mitochondrial regulation of functional pathways in the brain affected in an animal model for adolescent binge drinking of ethanol. Determining of targets for treatment of ethanol induced brain damage |
Graziano Pesole / Oscar Della Pasqua |
Positive |
| Saul Yedgar (External user) |
Dept. of Biochemistry, Hebrew University Faculty of Medicine, Israel |
To develop a diagnostic approach to reduce the risk of pathology in preterm newborns |
Giovanni Migliaccio |
Positive |
| Nunzio Denora (Internal user) |
Department of Pharmacy – Pharmaceutical Sciences, University of Bari, Italy |
Paediatric oral liquid formulations of sodium dichloroacetate for the acute and chronic treatment of acquired or congenital lactic acidosis |
Catherine Tuleu / Adriana Ceci |
Positive |
