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Feasibility Studies Received


Emmanuel Mikros (Internal user) Research and Innovation Center in Information Communication & Knowledge Technologies (ATHENA), Greece Discovery of new therapeutic agents for the treatment of Duchenne muscular dystrophy Dimitrios Athanasiou / Catherine Knibbe Positive
Marina Kleanthous (Internal User) Cyprus Institute of Neurology and Genetics (CING), Cyprus Identification of biomarkers for the segregation of paediatric beta thalassaemia patients responding to drug Hydroxyurea Oscar Della Pasqua / Dimitrios Athanasiou Positive
Evelyne Jacqz-Aigrain, Saskia de Wildt (Internal users) Department of pharmacology and pharmacogenetics – Assistance Publique – Hôpitaux de Paris (AP-HP), France, Department of Pharmacology-Toxicology – Radboud University Medical center (RUMC), The Netherlands Melatonin administered during pregnancy as a potential neuroprotective agent against neonatal brain damage Adriana Ceci / Catherine Tuleu Positive
Catherine Tuleu (Internal user) School of Pharmacy – University College London (UCL), UK Preparing a newly developed active pharmaceutical ingredient (API) for Phase 1 trials: enhancing the solubility for better bioavailability, improving the taste to allow its formulation into a wide range of oral dosage forms and assessing modifications carried out to validate the solubility and taste improvements made Giovanni Migliaccio / Catherine Knibbe Positive
Claudia Scotti (External user) Department of Molecular Medicine, Unit of Immunology and General Pathology, University of Pavia, Italy A protease-resistant Escherichia coli asparaginase with outstanding stability and enhanced anti-leukaemic activity in vitro: from bench to bedside Graziano Pesole / Oscar Della Pasqua Positive
Giuseppe Pontrelli, Oscar Della Pasqua (Internal users) Bambino Gesù Paediatric Hospital (OPBG), Italy, Clinical Pharmacology – University College London (UCL), UK MoSe2. Improved diagnosis and model-based dosing algorithms for antibiotic therapy in neonatal and paediatric sepsis. Adriana Ceci / Dimitrios Athanasiou Positive
Claudio Franceschi (External user) University of Bologna, Italy Precision Personalized Paediatric neuroPsychiatry (4P) Giovanni Migliaccio / Dimitrios Athanasiou Positive
Moshe Gavish (Internal user) Faculty of Medicine, Rappaport Institute for Research in the Medical Sciences – Technion, Israel Institute of Technology, Israel Mitochondrial regulation of functional pathways in the brain affected in an animal model for adolescent binge drinking of ethanol. Determining of targets for treatment of ethanol induced brain damage Graziano Pesole / Oscar Della Pasqua Positive
Saul Yedgar (External user) Dept. of Biochemistry, Hebrew University Faculty of Medicine, Israel To develop a diagnostic approach to reduce the risk of pathology in preterm newborns Giovanni Migliaccio Positive
Nunzio Denora (Internal user) Department of Pharmacy – Pharmaceutical Sciences, University of Bari, Italy Paediatric oral liquid formulations of sodium dichloroacetate for the acute and chronic treatment of acquired or congenital lactic acidosis Catherine Tuleu / Adriana Ceci Positive